The use of NPWT in combination with silver dressing in diabetic foot syndrome – case report
Patients with diabetes mellitus are at increased risk of angiopathy, neuropathy and infection compared with healthy individuals and that may lead to foot disorders. Treatment is difficult challenging and if it is not successful it often run to lower limbs amputations.
We present case report of 63 years old man after amputation of big toe and part of metatarsus due to diabetic foot syndrome, successfully treated with negative pressure wound therapy in combination with silver dressing. The literature regarding this issue was also reviewed.
Frykberg RG, Zgonis T, Armstrong DG, Driver VR, Giurini JM, Kravitz SR, Landsman AS, Lavery LA, Moore JC, Schuberth JM, Wukich DK, Andersen C, Vanore JV; American College of Foot and Ankle Surgeons. Diabetic foot disorders. A clinical practice guideline (2006 revision). The Journal of foot and ankle surgery 2006;45(5 Suppl):S1-66.
Ebskov LB. Diabetic amputation and long-term survival. International journal of rehabilitation research 1998;21(4):403-8.
da Rosa LM, Radünz, V. Survival rates to woman with breast cancer: review. Texto & Contexto - Enfermagem 2012;21(4):980-989.
DeSantis C, Ma J, Bryan L, Jemal A. Breast cancer statistics, 2013. CA: a cancer journal for clinicians. 2014;64(1):52-62.
Vig S, Dowsett C, Berg L, Caravaggi C, Rome P, Birke-Sorensen H, Bruhin A, Chariker M, Depoorter M, Dunn R, et al. Evidence-based recommendations for the use of negative pressure wound therapy in chronic wounds: steps towards an international consensus. Journal of tissue viability 2011;20 Suppl 1:S1-18.
Armstrong DG, Lavery LA, for the Diabetic Foot Study Consortium. Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomized controlled trial. Lancet 2005(9498); 366:1704–10.
Stinner DJ, Waterman SM, Masini BD, Wenke JC. Silver dressings augment the ability of negative pressure wound therapy to reduce bacteria in a contaminated open fracture model. The Journal of trauma 2011;71(1 Suppl):S147-50.
Krokowicz L, Borejsza-Wysocki M, Mackiewicz J, Iqbal A, Drews M. 10 years of negative pressure wound therapy (NPWT). Negative Pressure Wound Therapy 2014;1(1):27–32.
Walczak DA, Jaguścik R, Porzeżyńska J, Fałek W, Czerwińska M, Ptasińska K, Kozaczek L, Krajewska B, Trzeciak PW. Negative pressure wound therapy in the treatment of a large chronic venous leg ulceration - as a perfect method for quick wound bed preparation and support for skin grafts healing. Negative Pressure Wound Therapy 2014;1(3):81-5.
Malmsjö M, Ingemansson R, Martin R, Huddleston E. Negative- pressure wound therapy using gauze or open-cell polyurethane foam: Similar early effects on pressure transduction and tissue contraction in an experimental porcine wound model. Wound repair and regeneration 2009;17(2):200-5
Kairinos N, Voogd AM, Botha PH, Kotze T, Kahn D, Hudson DA, Solomons M. Negative-pressure wound therapy II: negative- pressure wound therapy and increased perfusion. Just an illusion? Plastic and reconstructive surgery 2009;123(2):601-12.
Greene AK, Puder M, Roy R, Arsenault D, Kwei S, Moses MA, Orgill DP. Microdeformational wound therapy: effects on angiogenesis and matrix metalloproteinases in chronic wounds of 3 debilitated patients. Annals of plastic surgery 2006;56(4):418-22.
Walczak DA, Jaguścik R, Porzeżyńska J, Ptasińska K, Kozaczek L, Krajewska B, Trzeciak PW. Large venous ulcers treated with negative pressure wound therapy – case report. Negative Pressure Wound Therapy 2014;1(3):100-3.
Novak A, Khan WS, Palmer J. The evidence-based principles of negative pressure wound therapy in trauma & orthopedics. The Open Orthopaedics Journal 2014;27(8):168-77.
Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Annals of plastic surgery 1997;38:553–62.
Edwards R, Harding KG. Bacteria and wound healing. Current opinion in infectious diseases 2004;17(2) 91–6.
Birke-Sorensen H, Malmsjo M, Rome P, Hudson D, Krug E, Berg L, Bruhin A, Caravaggi C, Chariker M, Depoorter M, Dowsett C, Dunn R, et al. Evidence-based recommendations for negative pressure wound therapy: treatment variables (pressure levels, wound filler and contact layer)--steps towards an international consensus. Journal of plastic, reconstructive, and aesthetic surgery 2011;64 Suppl:S1-16.
Mouës CM, Vos MC, van den Bemd GJ, Stijnen T, Hovius SE. Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial. Wound repair and regeneration 2004;12(1):11-7.
Khashram M, Huggan P, Ikram R, Chambers S, Roake JA, Lewis DR. Effect of TNP on the microbiology of venous leg ulcers: a pilot study. Journal of wound care 2009;18(4):164-7.
Weed T, Ratliff C, Drake DB. Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance? Annals of plastic surgery 2004;52(3):276-9; discussion 279-80.
Mueller S, Krebsbach L. Impact of an antimicrobial impregnated gauze dressing on surgical site infections including methicillin-resistant Staphylococcus aureus infections. American journal of infection control 2008;36(9):651-5.
Kim PJ, Attinger CE, Steinberg JS, Evans KK, Lehner B, Willy C, Lavery L, Wolvos T, Orgill D, Ennis W, Lantis J, Gabriel A, Schultz G. Negative-pressure wound therapy with instillation: international consensus guidelines. Plastic and reconstructive surgery 2013;132(6):1569-79.
Richards AJ, Hagelstein SM, Patel GK, Ivins NM, Sweetland HM, Harding KG. Early use of negative pressure therapy in combination with silver dressings in a difficult breast abscess. International wound journal 2011;8(6):608-11.
Gerry R, Kwei S, Bayer L, Breuing KH.. Silver-impregnated vacuum assisted closure in the treatment of recalcitrant venous stasis ulcers Annals of plastic surgery 2007;59(1):58-62.
Zou SB, Yoon WY, Han SK, Jeong SH, Cui ZJ, Kim WK. Cytotoxicity of silver dressings on diabetic fibroblasts. International Wound Journal 2013;10(3):306-12.
Gabriel A, Shores J, Bernstein B, de Leon J, Kamepalli R, Wolvos T, Baharestani MM, Gupta S. A clinical review of infected wound treatment with Vacuum Assisted Closure (V.A.C.) therapy: experience and case series. International Wound Journal 2009;6 Suppl 2:1-25.
Siegel HJ, Herrera DF, Gay J. Silver negative pressure dressing with vacuum-assisted closure of massive pelvic and extremity wounds. Clinical Orthopedics and Related Research 2014;472(3):830-5.
Leaper DJ. Silver dressings: their role in wound management. International Wound Journal 2006;3(4):282-94.
Copyright (c) 2014 Dominik Andrzej Walczak, Rajmund Jaguścik, Karolina Ptasińska, Leokadia Kozaczek, Piotr Wojciech Trzeciak
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
We require authors to sign a Publication Agreement prior to publication of the manuscript in NPWTJ. The link to this form may be found below.
PUBLICATION AGREEMENT FORM